Search results for "Tumor size"

showing 10 items of 23 documents

Treatment of clinically localized renal tumors in the elderly

2011

There are several options for treating clinically localized renal tumors in the elderly, ranging from active surveillance to radical nephrectomy. Reduced renal function is associated with increased cardiovascular mortality, so maintaining renal function is of the utmost importance. Personalized therapy should be based on tumor location, comorbidities and general health status rather than tumor size and patient age.

medicine.medical_specialtyTumor sizebusiness.industryUrologymedicine.medical_treatmentUrologyRenal functionurologic and male genital diseasesmedicine.diseaseNephrectomymedicineGeneral healthTumor locationPersonalized therapybusinessKidney cancerCardiovascular mortalityNature Reviews Urology
researchProduct

Robotic Versus Laparoscopic Gastric Resection for Primary Gastrointestinal Stromal Tumors5 cm: A Size-Matched and Location-Matched Comparison.

2017

This study compared robotic (RR) and laparoscopic resection (LR) for primary gastrointestinal stromal tumors (GISTs) of the stomach >5 cm. Twelve consecutive patients who underwent RR from 2012 to 2015 were matched for tumor size and location with 24 patients who underwent LR from 2000 to 2012. The median tumor size was 7.1 cm (range, 5.5 to 11.5). GISTs were resected by wedge resection (91.7%) or distal gastrectomy. The median RR operative time was longer than that of LR (162.5 vs. 130 min, respectively; P=0.004). Only 1 LR patient required conversion. The time to flatus and hospital stay were similar between groups. Overall, 3 patients developed minor postoperative complications that w…

AdultMalemedicine.medical_specialtyStromal cellGastrointestinal Stromal TumorsOperative TimeBlood Loss Surgical030230 surgeryRobotic gastric resectionRisk Assessment03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRobotic Surgical ProceduresStomach Neoplasmslaparoscopic gastric resectionmedicineHumansLaparoscopic resectionGastric resectionUltrasonography InterventionalAgedAged 80 and overTumor sizebusiness.industryStomachIncidence (epidemiology)Length of StayMiddle AgedSurgerySettore MED/18 - Chirurgia Generalemedicine.anatomical_structureTreatment OutcomeSurgery Computer-Assisted030220 oncology & carcinogenesisCosts and Cost AnalysisOperative timeSurgeryFemaleLaparoscopybusinessprimary gastrointestinal stromal tumorGISTWedge resection (lung)Surgical laparoscopy, endoscopypercutaneous techniques
researchProduct

Factors associated with epiphora following orbital‐sparing maxillectomy via modified Weber–Ferguson incision with lower blepharoplasty

2021

Purpose The aims of the study were to estimate the frequency of epiphora and to identify factors associated with epiphora after orbital-sparing maxillectomy via modified Weber-Ferguson incision with lower blepharoplasty (OSOSM-MWFILB). Methods We performed a retrospective cohort study enrolling a sample derived from the patient population undergoing OSM-MWFILB over a 7-year period. The predictor variables were grouped into demographic, related health status, anatomic, tumor-specific, and therapeutic categories. The primary outcome variable was the presence of postmaxillectomy epiphora (PME). Descriptive, univariate, and multivariate regression mixed-effect models were computed. Results The …

AdultBlepharoplastyMaleBlepharoplastymedicine.medical_specialtyMultivariate statisticsmedicine.medical_treatment03 medical and health sciences0302 clinical medicineNeoplasmsMaxillamedicineOperating timeHumansIn patientAgedRetrospective StudiesAged 80 and overLacrimal Apparatus DiseasesTumor sizebusiness.industryUnivariateRetrospective cohort studyGeneral MedicineMiddle AgedPrognosisSurgeryOncology030220 oncology & carcinogenesisCarcinoma Squamous CellFemale030211 gastroenterology & hepatologySurgerybusinessComplicationOrbitOrgan Sparing TreatmentsFollow-Up StudiesJournal of Surgical Oncology
researchProduct

Imperative and Elective Indications for Nephron-Sparing Surgery for Renal Tumors: Long-Term Oncological Follow-Up

2010

INTRODUCTION: Nephron-sparing surgery (NSS) is mandatory for patients with renal tumors in both kidneys or in a solitary kidney in order to preserve renal function (imperative indication). NSS has also become the gold standard (elective indication) for small unilateral renal tumors (< 4 cm) with a normal contralateral kidney. We report the oncological long-term follow-up of NSS of our own series and discuss the results of the current literature. PATIENTS AND METHODS: From 1979 until 2006, a total of 851 patients was treated at our institu-tion by NSS. The mean tumor diameter was 3 cm (0.5-11 cm) for elective cases and 4.2 cm (1.2-11 cm) for imperative cases. The median follow-up for electiv…

Reoperationmedicine.medical_specialtyUrologySolitary kidneyRenal functionNephrectomyDisease-Free SurvivalNeoplasms Multiple PrimaryPostoperative ComplicationsRenal cell carcinomamedicineHumansCarcinoma Renal CellRetrospective StudiesTumor sizebusiness.industryGold standardNephronsmedicine.diseaseKidney NeoplasmsSurgeryElective Surgical ProceduresKidney Failure ChronicChronic renal failureBoth kidneysNephron sparing surgeryNeoplasm Recurrence LocalbusinessFollow-Up StudiesAktuelle Urologie
researchProduct

EP756 Laterally extended endopelvic resection: a comparative analysis between laparotomic and laparoscopically modified approach

2019

Introduction/Background Laterally Extended Endopelvic Resection (LEER) has been identified as a valid therapeutic option for women with gynecological malignancies involving the pelvic side wall. The historical approach to LEER is laparotomic, recently we have proposed the so called Laparoscopically Modified Laterally Extended Endopelvic Resection (LM-LEER).The objective of this study is to compare surgical and oncological outcomes between LEER and LM-LEER in a consecutive series of patients with gynecological malignancies infiltrating the pelvic side wall. Methodology We retrospectively evaluated women submitted to LEER between October 2012 and January 2019. Inclusion criteria for LM-LEER w…

High ratemedicine.medical_specialtyTumor sizebusiness.industryTumor resectionMedicineOperative timePerioperativebusinessShort intervalResectionSurgeryePoster
researchProduct

Distal pancreatectomy with multivisceral resection: A retrospective multicenter study - Case series.

2020

Abstract Background Multivisceral resection (MVR) is sometimes necessary to achieve disease-free margins in cancer surgery. In certain patients with pancreatic tumors that invade neighboring organs these must be removed to perform an appropriate oncological surgery. In addition, there is an increasing need to perform resections of other organs like liver not directly invaded by the tumor but which require synchronous removal. The results of MVR in pancreatic surgery are controversial. Material and methods A distal pancreatectomy retrospective multicenter observational study using prospectively compiled data carried out at seven HPB Units. The period study was January 2008 to December 2018. …

AdultMalemedicine.medical_specialty030230 surgery03 medical and health sciencesPancreatic Fistula0302 clinical medicinePancreatectomyBlood lossmedicineHumansAgedRetrospective StudiesTumor sizebusiness.industryMultivisceral resectionCancerGeneral MedicineMiddle Agedmedicine.diseaseSurgeryPancreatic Neoplasmsmedicine.anatomical_structureMulticenter studyPancreatic fistula030220 oncology & carcinogenesisSurgeryFemaleMorbidityPancreasDistal pancreatectomybusinessInternational journal of surgery (London, England)
researchProduct

Changes in hepatocellular carcinoma aggressiveness characteristics with an increase in tumor diameter

2021

Background: Hepatocellular carcinoma prognosis depends on both liver and tumor determinants, especially on maximum tumor diameter, multifocality, and presence of portal vein thrombosis, despite apparently complete tumor removal by resection or liver transplantation. Aims: To examine parameters of hepatocellular carcinoma aggressiveness as tumor size increases. Methods: A large hepatocellular carcinoma database was examined for trends in serum alpha-fetoprotein and the percentage of patients with macroscopic portal vein thrombosis or tumor multifocality. Results: A total of 13,016 hepatocellular carcinoma patients were identified having full tumor and survival data. Of these, 76.56% were mal…

MaleCancer ResearchPathologymedicine.medical_specialtyCarcinoma HepatocellularPrognosiSettore MED/12 - GASTROENTEROLOGIAClinical BiochemistrysizePathology and Forensic MedicineevolutionmedicineHumansProspective StudiesHCCTumor sizebusiness.industryLiver NeoplasmsCarcinomaSettore MED/09 - MEDICINA INTERNAHepatocellularMiddle AgedPrognosismedicine.diseasePortal vein thrombosisHCC; evolution; size; trendtrendOncologyLiver NeoplasmHepatocellular carcinomaevolution; HCC; size; trendFemalebusinessHuman
researchProduct

Conservative surgery of renal cell carcinoma.

1986

Abstract From 1967 to 1985 conservative surgery (enucleation, n = 49; partial resection, n = 7) was performed for renal tumors in 57 patients (age 31-77, mean 54.8 years). Imperative indications for conservative surgery (n = 29) were chronic renal failure, benign pathology of contralateral kidney, functional or anatomical solitary kidney, and bilateral tumors. Elective conservative surgery (n = 28) was done for small, peripherally located lesions, in cases of uncertain malignancy and in one tumor detected by chance during stone surgery. Tumors removed for imperative indications were 2-11 cm (mean 5.8 cm) in size. In the elective group, tumor size ranged from 1 to 7 cm (mean 3.3 cm). Follow-…

AdultMalemedicine.medical_specialtyUrologySolitary kidneyEnucleationMalignancyBenign pathologyPostoperative ComplicationsRenal cell carcinomaMethodsMedicineHumansCarcinoma Renal CellAgedTumor sizebusiness.industryCancerPartial resectionMiddle Agedmedicine.diseasePrognosisKidney NeoplasmsSurgeryFemalebusinessEuropean urology
researchProduct

Radiotherapy for the treatment of solitary plasmacytoma: 7-year outcomes by a mono-institutional experience.

2020

Objectives: Solitary plasmacytoma (SP) is characterized by a single mass of clonal plasma cells. Definitive RT can result in long-term local control of the SP. Due to the small number of patients and narrow range of doses, phase III randomized trials are lacking. The aim of this study is to further support the potential use of RT for the treatment of SP. Methods: Clinical data of all patients treated for SP at our Institution between 1992 and 2018 were reviewed. A total of 42 consecutive patients were analyzed. Results: The median follow-up was 84.8 months. Radiation dose did not differ significantly as a function of sex, type of SP (solitary bone plasmacytoma or as extramedullary plasmacyt…

0301 basic medicineAdultMaleCancer Researchmedicine.medical_specialtymedicine.medical_treatmentUrologySolitary plasmacytomaBone NeoplasmsMultiple myeloma; Plasma cell neoplasms; Radical radiotherapy; Solitary plasmacytomaEffective dose (radiation)law.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawInternal medicinemedicineHumansMultiple myelomaAgedRetrospective StudiesAged 80 and overHematologyRadical radiotherapyTumor sizebusiness.industryGeneral MedicinePlasma cell neoplasmMiddle Agedmedicine.diseasePrognosisSurvival AnalysisRadiation therapyPlasma cell neoplasm030104 developmental biologyTreatment OutcomeOncologyItaly030220 oncology & carcinogenesisDisease ProgressionFemalePlasma cell neoplasmsNeoplasm Recurrence LocalbusinessMultiple MyelomaSolitary plasmacytomaFollow-Up StudiesPlasmacytomaJournal of cancer research and clinical oncology
researchProduct

Intrahepatic cholangiocarcinoma: Introducing the preoperative prediction score based on preoperative imaging.

2020

Intrahepatic cholangiocarcinoma (ICC) still has a poor long-term outcome, even after complete resection. We investigated different parameters gathered in preoperative imaging and analyzed their influence on resectability, recurrence, and survival.All patients who underwent exploration due to ICC between January 2008 and June 2018 were analyzed retrospectively. Kaplan-Meier model, log-rank test and Cox regression were used.Out of 184 patients, 135 (73.4%) underwent curative intended resection. Median overall survival (OS) was 22.2 months with a consecutive 1-, 3- and 5-year OS of 73%, 29%, and 17%. Median recurrence-free survival (RFS) was 9.3 months with a consecutive 1-, 3- and 5-year RFS …

medicine.medical_specialtyPrediction scoreUnivariate analysisHepatologyTumor sizeProportional hazards modelbusiness.industryGastroenterology030230 surgeryPrognosisComplete resectionCholangiocarcinoma03 medical and health sciences0302 clinical medicineRisk groupsBile Ducts IntrahepaticBile Duct NeoplasmsmedicineHumans030211 gastroenterology & hepatologyRadiologybusinessIntrahepatic CholangiocarcinomaPreoperative imagingRetrospective StudiesHepatobiliarypancreatic diseases international : HBPD INT
researchProduct